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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIBCH
All Species:
10.61
Human Site:
T249
Identified Species:
16.67
UniProt:
Q6NVY1
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NVY1
NP_055177.2
386
43482
T249
S
V
L
E
N
Y
H
T
E
S
K
I
D
R
D
Chimpanzee
Pan troglodytes
XP_515988
440
48807
T303
S
V
L
E
N
Y
H
T
E
S
K
I
D
R
D
Rhesus Macaque
Macaca mulatta
XP_001103467
444
49874
T307
S
V
L
E
N
Y
H
T
E
S
K
I
D
R
D
Dog
Lupus familis
XP_848689
359
39946
S231
S
K
I
D
Q
D
K
S
F
I
L
E
E
H
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8QZS1
385
43019
A248
G
V
L
E
S
Y
H
A
K
S
K
M
D
Q
D
Rat
Rattus norvegicus
Q5XIE6
385
43006
A248
G
V
L
E
S
Y
H
A
K
S
K
M
G
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJ60
385
42810
M248
D
L
L
N
S
Y
H
M
Q
T
K
I
D
Q
E
Frog
Xenopus laevis
A2VDC2
385
42348
K248
D
V
L
D
S
Y
Q
K
K
S
Y
A
A
Q
D
Zebra Danio
Brachydanio rerio
Q58EB4
382
42258
E245
Q
L
L
D
S
Y
Q
E
Q
S
H
L
D
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650453
385
42729
P253
L
Q
K
Y
H
S
P
P
E
K
P
F
S
L
Q
Honey Bee
Apis mellifera
XP_396249
396
44074
L254
N
K
Y
Q
S
K
T
L
N
Q
E
F
C
L
A
Nematode Worm
Caenorhab. elegans
P34559
288
31153
Q160
G
E
K
A
R
F
G
Q
P
E
I
N
I
G
T
Sea Urchin
Strong. purpuratus
XP_791196
379
41899
Q242
Q
V
L
Q
K
F
H
Q
Q
C
S
I
D
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q1PEY5
378
42237
I246
S
K
R
T
V
E
E
I
F
S
A
L
E
R
E
Baker's Yeast
Sacchar. cerevisiae
P28817
500
56270
A252
F
N
N
D
P
Q
S
A
Y
F
F
G
M
V
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.8
84.9
84.4
N.A.
81.8
81.6
N.A.
N.A.
69.1
69.6
65.2
N.A.
49.2
47.9
24.6
56.9
Protein Similarity:
100
86.8
86.2
87.8
N.A.
92.2
92.2
N.A.
N.A.
83.9
81.3
78.2
N.A.
67.6
67.1
40.9
75.1
P-Site Identity:
100
100
100
6.6
N.A.
60
53.3
N.A.
N.A.
40
33.3
26.6
N.A.
6.6
0
0
40
P-Site Similarity:
100
100
100
33.3
N.A.
86.6
80
N.A.
N.A.
80
60
66.6
N.A.
13.3
26.6
6.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.1
30.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.8
47
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
20
0
0
7
7
7
14
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
7
0
0
% C
% Asp:
14
0
0
27
0
7
0
0
0
0
0
0
47
0
47
% D
% Glu:
0
7
0
34
0
7
7
7
27
7
7
7
14
0
20
% E
% Phe:
7
0
0
0
0
14
0
0
14
7
7
14
0
0
0
% F
% Gly:
20
0
0
0
0
0
7
0
0
0
0
7
7
7
0
% G
% His:
0
0
0
0
7
0
47
0
0
0
7
0
0
7
0
% H
% Ile:
0
0
7
0
0
0
0
7
0
7
7
34
7
0
0
% I
% Lys:
0
20
14
0
7
7
7
7
20
7
40
0
0
0
0
% K
% Leu:
7
14
60
0
0
0
0
7
0
0
7
14
0
14
0
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
14
7
0
7
% M
% Asn:
7
7
7
7
20
0
0
0
7
0
0
7
0
0
7
% N
% Pro:
0
0
0
0
7
0
7
7
7
0
7
0
0
0
0
% P
% Gln:
14
7
0
14
7
7
14
14
20
7
0
0
0
27
7
% Q
% Arg:
0
0
7
0
7
0
0
0
0
0
0
0
0
27
0
% R
% Ser:
34
0
0
0
40
7
7
7
0
54
7
0
7
0
0
% S
% Thr:
0
0
0
7
0
0
7
20
0
7
0
0
0
0
7
% T
% Val:
0
47
0
0
7
0
0
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
0
54
0
0
7
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _